关于这个问题，分歧比较多，国内如此，国外也是如此。保守一些的大夫认为羟化氯喹类药对患者有什么副作用对婴儿也存在同样的潜在的危害，主要是眼睛方面；另外一些大夫则认为应当没有危害。所以现实情况是有的患者在医生的指导下停了羟化氯喹类药再怀孕，有的患者则在怀孕的过程中坚持服用，目前应当是没有异常报告。大家可以看看下面的帖子－－主要讨论强的松和羟化氯喹对怀孕的影响，摘自国外一个论坛。
! ^0 `4 O0 A3 I t4 \: Jhttp://www.healthboards.com/boards/showthread.php?t=372569
4 \: d. s1 {! F* E7 f% x2 p1 x% V简单总结如下：) Y% `! V+ a% [! Y& K
1.大多数大夫认为怀孕期间服用少量的激素是安全的。+ g |( h" i( X/ T
2.对于纷乐，一部分大夫认为如果有条件应当停掉，另外一部分认为是安全的。3 G- m9 z8 a9 p- }2 {: R% {: G! n
有患者怀孕期间服用，未出现异常。
/ a5 I$ }5 k) a+ R: F# `3. 从WebMD上面的一些文献来说，认为羟化氯喹对怀孕是安全的：2 q* A+ O9 R: g) p: f0 ?( B5 y$ l
Prednisone, for example, is generally considered safe during pregnancy. Hydroxychloroquine (Plaquenil) and sulfasalazine are also considered safe. While evidence is limited for biologic medicines like Enbrel and Remicade, many rheumatologists are confident in their relative safety during pregnancy.
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Immunosuppressant medications, which may be prescribed for severe lupus, can cause birth defects. Do not take immunosuppressants if you are pregnant or wish to become pregnant.7 [% t9 d- t) U6 r# p0 A# d7 }
Corticosteroids (such as prednisone) are generally considered safe for use during pregnancy because they do not reach the fetus in an active form.2
9 P+ r0 m- @; q1 U4 D! cCytotoxic medications such as methotrexate are stopped during pregnancy. They should be discontinued several months before conception.# H# W% Y3 H+ a1 J) g& U- I9 @! q8 a0 F) x
Recent studies suggest that hydroxychloroquine (Plaquenil) is safe for use during pregnancy.3+ F: K7 M7 D; p
Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and aspirin should be avoided during pregnancy unless prescribed by a doctor
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建议和自己的主治大夫再沟通。 |
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发表于 2008-11-7 15:02:24
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发表于 2008-11-13 23:10:01