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发表于 2008-12-3 09:53:42
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105-9-第九节 预 后
本病为慢性进行性皮肤关节病变,具体生存率不清。虽然早期诊断后激素及免疫抑制剂的使用和积极的外科治疗使预后得到改善,但仍有45%患者因合并严重关节病变,遗留关节残疾。另外 25%一30%患者合并肿瘤,预后差。Ka等随诊一例具有 20年病程的患者,由于一直未接受正规治疗,周身皮疹及严重关节破坏畸形的同时出现心脏病变,给予治疗后好转。目前认为对于未合并肿瘤的患者,往往在病程最初的几年内关节及皮肤病变活动并可能出现严重受损,晚期患者可能进人疾病慢性进展期,治疗后病情可能出现缓解而长期存活。 # M( |8 w4 h) m3 h& F) z
( 薛 静 于孟学 )
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