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发表于 2008-12-10 08:52:35
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73-6-第六节 预 后
90%的MPA患者经治疗能得到改善,75%的患者能完全缓解,约30%的患者在1--2年后复发。本病治疗后的2年和5年生存率大约为75%和74 。与PAN相似,本病的主要死亡原因是不能控制的病情活动、肾功能衰竭和继发感染以及肺脏受累。北京协和医院确诊的MPA中有2例在住院期间死亡,病因为急进性肾小球性肾炎(rapidly progressiveglomerulonephritis, RPGN )、弥散性肺泡出血和败血症。疾病过程中应密切监测 ESR水平,MPA中ANCA的滴度与病情活动相关性较差。
7 p: g# i. a$ c/ C ( 曾小峰 艾脉兴 )
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