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37-6-第六节 贝赫切特病
贝赫切特病(Behcet病)是一种以口腔溃疡、会阴部溃疡和眼色素膜炎为主要特征的慢性、反复发作的炎性疾病。血管炎是其基本的病理基础,病因还不清楚。自从土耳其皮科医师Behcet于1937年首先描述此病以后,世界各地已有很多病例报告,其中以地中海沿岸、阿拉伯国家、日本等地的发病率较高,我国亦较常见。 ( ?" K6 L# I7 t3 I5 _. t2 I6 r, k
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现知贝赫切特病是一全身性疾病,其临床表现除了口、眼、会阴三联症反复发作之外,可以侵及周身多种器官,消化系统也是常受损害的部位。贝赫切特病患者自口腔到直肠均可发生溃疡。食管溃疡除了局部明显疼痛外,可因炎性狭窄而出现吞咽困难。有人报告,贝赫切特病亦可伴有责门失弛张症样的表现,出现明显的吞咽困难症状。此病患者的肠道溃疡发生在回肠和回肠末端者比较常见,可因此而并发出血和穿孔。溃疡发生在结肠者也并不少见。贝赫切特病并发肠道溃疡时,易与克罗恩病相混淆,有时不易鉴别。 7 c0 a) r2 J: N: x, M
( 陈寿坡 吴克林 陈志强 )
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