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28-8-第八节 混合性结缔组织病
混合性结缔组织病(mixed connective tissue disease, MCTD)是指多种免疫性疾病同时共存,如SLE、多发性肌炎、系统性硬化及高滴度抗含有 U1 RNP颗粒的RNP抗体。 3 h8 J& z4 Z3 j2 k* V
. [% O& N3 t L- H: D' T: { 混合性结缔组织病可表现关节炎、手肿胀、雷诺现象、食管运动异常、肌炎、白细胞减少及贫血、发热、淋巴结肿大、高球蛋白血症。这些表现提示为SLE、多发性肌炎及系统性硬化。这种多重疾病的发生并不完全清楚,大多数学者认为混合性结缔组织病不是一种特殊的疾病。 6 r3 F/ V( u @4 h- Z, V% [) E
( 陈杰 崔全才 )
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